Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution.

Using information gained from (i) the relative HPLC retention of an abnormal insulin present in the serum of a hyperinsulinemic diabetic patient and (ii) the loss of an Mbo II restriction site in one of the patient's insulin gene alleles, it was recently predicted that the mutant insulin contai...

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Bibliographic Details
Main Authors: Shoelson, S, Fickova, M, Haneda, M, Nahum, A, Musso, G, Kaiser, E T, Rubenstein, A H, Tager, H
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC389956/
https://ncbi.nlm.nih.gov/pubmed/6424111
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