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Nanopore-based identification of individual nucleotides for direct RNA sequencing
We describe a label-free ribobase identification method, which uses ionic current measurement to resolve ribonucleoside monophosphates or diphosphates in α-hemolysin protein nanopores containing amino-cyclodextrin adapters. The accuracy of base identification is further investigated through the use...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899427/ https://ncbi.nlm.nih.gov/pubmed/24171554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl403469r |
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