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Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

BACKGROUND: Adoptive transfer of T cells genetically engineered with a chimeric antigen receptor (CAR) has successfully been used to treat both chronic and acute lymphocytic leukemia as well as other hematological cancers. Experimental therapy with CAR-engineered T cells has also shown promising res...

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Hlavní autoři: Hillerdal, Victoria, Ramachandran, Mohanraj, Leja, Justyna, Essand, Magnus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899402/
https://ncbi.nlm.nih.gov/pubmed/24438073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-30
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