Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus.
Using genetically engineered glomerular mesangial cells, an in vivo gene transfer approach was developed that specifically targets the renal glomerulus. By combining this system with a tetracycline (Tc)-responsive promoter, the present study aimed to create a reversible on/off system for site-specif...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8693003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7387 |
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