Engineering an Effective Immune Adjuvant by Designed Control of Shape and Crystallinity of Aluminum Oxyhydroxide Nanoparticles

Adjuvants based on aluminum salts (Alum) are commonly used in vaccines to boost the immune response against infectious agents. However, the detailed mechanism of how Alum enhances adaptive immunity and exerts its adjuvant immune effect remains unclear. Other than being comprised of micron-sized aggr...

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Bibliografiske detaljer
Main Authors: Sun, Bingbing, Ji, Zhaoxia, Liao, Yu-Pei, Wang, Meiying, Wang, Xiang, Dong, Juyao, Chang, Chong Hyun, Li, Ruibin, Zhang, Haiyuan, Nel, André E., Xia, Tian
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899397/
https://ncbi.nlm.nih.gov/pubmed/24261790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn404211j
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