NADPH Oxidase Dependent NLRP3 Inflammasome Activation Plays an Important Role in Lung Fibrosis by Multi-Walled Carbon Nanotubes

The purpose of this communication is to elucidate the key role of NADPH oxidase in NLRP3 inflammasome activation and generation of pulmonary fibrosis by multi-walled carbon nanotubes (MWCNTs). Although it is known that oxidative stress plays a role in pulmonary fibrosis by single-walled CNTs, the ro...

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Published in:Small
Main Authors: Sun, Bingbing, Wang, Xiang, Ji, Zhaoxia, Wang, Meiying, Liao, Yu-Pei, Chang, Chong Hyun, Li, Ruibin, Zhang, Haiyuan, Nel, André E., Xia, Tian
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420651/
https://ncbi.nlm.nih.gov/pubmed/25581126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201402859
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