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Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species

The natural product embelin has been demonstrated to possess a wide range of therapeutic properties, however, the mechanisms by which it exerts anticancer effects are not yet clear. By monitoring the molecular changes associated during early apoptotic phase, we have identified the crucial role of ox...

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Detalhes bibliográficos
Main Authors: Avisetti, Deepa R., Babu, K. Suresh, Kalivendi, Shasi V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899364/
https://ncbi.nlm.nih.gov/pubmed/24466324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087050
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