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Identification of Two Wnt-Responsive Elements in the Intron of RING Finger Protein 43 (RNF43) Gene

RING finger protein 43 (RNF43), an E3-type ubiquitin ligase, is frequently up-regulated in human colorectal cancer. It has been shown that expression of RNF43 is regulated by the Wnt-signaling pathway. However the regulatory region(s) for its transcriptional activation has not been clarified. In thi...

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Détails bibliographiques
Auteurs principaux: Takahashi, Norihiko, Yamaguchi, Kiyoshi, Ikenoue, Tsuneo, Fujii, Tomoaki, Furukawa, Yoichi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899290/
https://ncbi.nlm.nih.gov/pubmed/24466159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086582
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