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Computation and Experiment Reveal that the Ring-Rearrangement Metathesis of Himbert Cycloadducts Can Be Subject to Kinetic or Thermodynamic Control

Unusual observations in the ring-rearrangement metathesis (RRM) of Himbert arene/allene cycloadducts to form fused polycylic lactams led to a more in-depth experimental study that yielded conflicting results. Differences in reactivity within related systems and unexpected changes in diastereoselecti...

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Autores principales: Lam, Jonathan K., Pham, Hung V., Houk, K. N., Vanderwal, Christopher D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899037/
https://ncbi.nlm.nih.gov/pubmed/24111571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja409618p
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