ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

This white paper provides a critical analysis of methods for estimating transporter kinetics and recommendations on proper parameter calculation in various experimental systems. Rational interpretation of transporter-knockout animal findings and application of static and dynamic physiologically base...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zamek-Gliszczynski, MJ, Lee, CA, Poirier, A, Bentz, J, Chu, X, Ellens, H, Ishikawa, T, Jamei, M, Kalvass, JC, Nagar, S, Pang, KS, Korzekwa, K, Swaan, PW, Taub, ME, Zhao, P, Galetin, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898877/
https://ncbi.nlm.nih.gov/pubmed/23588311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.45
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados