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Replication of Mitochondrial DNA in Mouse L Cells and Their Thymidine Kinase(-) Derivatives: Displacement Replication on a Covalently-Closed Circular Template

Thymidine kinase(-) lines of mouse L cells incorporate thymidine exclusively into mitochondrial DNA. This fact permits assessment of labeled mitochondrial DNA components in ethidium bromide-cesium chloride gradients. Contaminating nuclear DNA is unlabeled and need not be removed. Elimination of the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Robberson, Donald L., Clayton, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1972
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389878/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4509344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.12.3810
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