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Rational Design of a Biomimetic Cell Penetrating Peptide Library

Cell penetrating peptides have demonstrated potential to facilitate the cellular delivery of therapeutic molecules. Here we develop a set of 50 cell penetrating peptide based formulations with potential to deliver small interfering RNAs intracellularly. The transfection efficacy of siRNA containing...

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Détails bibliographiques
Auteurs principaux: Karagiannis, Emmanouil D., Urbanska, Aleksandra M., Sahay, Gaurav, Pelet, Jeisa M., Jhunjhunwala, Siddharth, Langer, Robert, Anderson, Daniel G.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898733/
https://ncbi.nlm.nih.gov/pubmed/24047542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn4027382
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