MicroRNA-26a is Strongly Down-regulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains (SODD)

Melanoma is an aggressive cancer that metastasizes rapidly, and is refractory to conventional chemotherapies. Identifying miRNAs that are responsible for this pathogenesis is therefore a promising means of developing new therapies. We identified miR-26a through microarray and qRT-PCR experiments as...

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Hauptverfasser: Reuland, Steven N., Smith, Shilo, Bemis, Lynne, Goldstein, Nathaniel B., Almeida, Adam, Partyka, Katie A, Marquez, Victor E., Zhang, Qinghong, Norris, David A., Shellman, Yiqun G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898712/
https://ncbi.nlm.nih.gov/pubmed/23190898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.400
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