The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock

Retinal photoreceptors entrain the circadian system to the solar day. This photic resetting involves cAMP response element binding protein (CREB)-mediated upregulation of Per genes within individual cells of the suprachiasmatic nuclei (SCN). Our detailed understanding of this pathway is poor, and it...

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Main Authors: Jagannath, Aarti, Butler, Rachel, Godinho, Sofia I.H., Couch, Yvonne, Brown, Laurence A., Vasudevan, Sridhar R., Flanagan, Kevin C., Anthony, Daniel, Churchill, Grant C., Wood, Matthew J.A., Steiner, Guido, Ebeling, Martin, Hossbach, Markus, Wettstein, Joseph G., Duffield, Giles E., Gatti, Silvia, Hankins, Mark W., Foster, Russell G., Peirson, Stuart N.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898689/
https://ncbi.nlm.nih.gov/pubmed/23993098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.004
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