VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis

Atherosclerosis is an inflammatory disease of the vascular wall. Activated monocytes and dendritic cells (DC) in the intima layer of the vasculature promote atherogenesis. Toll-like receptor (TLR)-2 and TLR-4, which are predominantly expressed on these cells and mediate their activation, are essenti...

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Detalhes bibliográficos
Main Authors: Mendel, I, Feige, E, Yacov, N, Salem, Y, Levi, I, Propheta-Meiran, O, Shoham, A, Ishai, E, George, J, Harats, D, Breitbart, E
Formato: Artigo
Idioma:Inglês
Publicado em: British Society for Immunology 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898561/
https://ncbi.nlm.nih.gov/pubmed/24116867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12212
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