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Treatment with lecinoxoids attenuates focal and segmental glomerulosclerosis development in nephrectomized rats
Focal segmental glomerulosclerosis (FSGS) is a scarring process associated with chronic low‐grade inflammation ascribed to toll‐like receptor (TLR) activation and monocyte migration. We developed synthetic, small‐molecule lecinoxoids, VB‐201 and VB‐703, that differentially inhibit TLR‐2‐ and TLR‐4‐m...
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| Publicado no: | Basic Clin Pharmacol Toxicol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7379519/ https://ncbi.nlm.nih.gov/pubmed/30125459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.13114 |
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