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Treatment with lecinoxoids attenuates focal and segmental glomerulosclerosis development in nephrectomized rats
Focal segmental glomerulosclerosis (FSGS) is a scarring process associated with chronic low‐grade inflammation ascribed to toll‐like receptor (TLR) activation and monocyte migration. We developed synthetic, small‐molecule lecinoxoids, VB‐201 and VB‐703, that differentially inhibit TLR‐2‐ and TLR‐4‐m...
Tallennettuna:
| Julkaisussa: | Basic Clin Pharmacol Toxicol |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7379519/ https://ncbi.nlm.nih.gov/pubmed/30125459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.13114 |
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