Shear-induced endothelial mechanotransduction: the interplay between reactive oxygen species (ROS) and nitric oxide (NO) and the pathophysiological implications

Hemodynamic shear stress, the blood flow-generated frictional force acting on the vascular endothelial cells, is essential for endothelial homeostasis under normal physiological conditions. Mechanosensors on endothelial cells detect shear stress and transduce it into biochemical signals to trigger v...

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Autori principali: Hsieh, Hsyue-Jen, Liu, Ching-Ann, Huang, Bin, Tseng, Anne HH, Wang, Danny Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898375/
https://ncbi.nlm.nih.gov/pubmed/24410814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-3
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