A Novel Closed-Head Model of Mild Traumatic Brain Injury Caused by Primary Overpressure Blast to the Cranium Produces Sustained Emotional Deficits in Mice

Emotional disorders are a common outcome from mild traumatic brain injury (TBI) in humans, but their pathophysiological basis is poorly understood. We have developed a mouse model of closed-head blast injury using an air pressure wave delivered to a small area on one side of the cranium, to create m...

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Autores principales: Heldt, Scott A., Elberger, Andrea J., Deng, Yunping, Guley, Natalie H., Del Mar, Nobel, Rogers, Joshua, Choi, Gy Won, Ferrell, Jessica, Rex, Tonia S., Honig, Marcia G., Reiner, Anton
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898331/
https://ncbi.nlm.nih.gov/pubmed/24478749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2014.00002
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