Motor, Visual and Emotional Deficits in Mice after Closed-Head Mild Traumatic Brain Injury Are Alleviated by the Novel CB2 Inverse Agonist SMM-189

We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in mice. As true for individuals that have experienced mild TBI, mice subjected to 50–60 psi blast show motor, visual and emotional deficits, diffuse axonal injury and microglial activation, but no overt neuron lo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Reiner, Anton, Heldt, Scott A., Presley, Chaela S., Guley, Natalie H., Elberger, Andrea J., Deng, Yunping, D’Surney, Lauren, Rogers, Joshua T., Ferrell, Jessica, Bu, Wei, Del Mar, Nobel, Honig, Marcia G., Gurley, Steven N., Moore, Bob M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307274/
https://ncbi.nlm.nih.gov/pubmed/25561230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16010758
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