Expression of Proteolipid Protein Gene in Spinal Cord Stem Cells and Early Oligodendrocyte Progenitor Cells Is Dispensable for Normal Cell Migration and Myelination

Plp1 gene expression occurs very early in development, well before the onset of myelination, creating a conundrum with regard to the function of myelin proteolipid protein (PLP), one of the major proteins in compact myelin. Using PLP-EGFP mice to investigate Plp1 promoter activity, we found that, at...

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Autori principali: Harlow, Danielle E., Saul, Katherine E., Culp, Cecilia M., Vesely, Elisa M., Macklin, Wendy B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898293/
https://ncbi.nlm.nih.gov/pubmed/24453324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2477-13.2014
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