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Genomic instability in pre-neoplastic colonic lesions

Genomic instability is a characteristic of most cancers and it is argued that genomic instability is a driving force for tumorigenesis. Data herein demonstrate that genomic instability, as evidenced by microsatellite instability (MSI) and promoter methylation of DNA mismatch repair genes, is common...

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Bibliografiska uppgifter
Huvudupphovsmän: Shaw, J A, Graham, T A, Stebbing, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898279/
https://ncbi.nlm.nih.gov/pubmed/23396367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.21
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