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A study of genomic instability in early preneoplastic colonic lesions

It is difficult to explain the differential rates of progression of premalignant colonic lesions and differences in behaviour of morphologically similar lesions. Heterogeneity for microsatellite instability (MSI) and promoter methylation in driving these phenomena forward may explain this; however,...

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Autors principals: Beggs, A D, Domingo, E, Abulafi, M, Hodgson, S V, Tomlinson, I P M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898108/
https://ncbi.nlm.nih.gov/pubmed/23246972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.584
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