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Biotechnological applications of mobile group II introns and their reverse transcriptases: gene targeting, RNA-seq, and non-coding RNA analysis

Mobile group II introns are bacterial retrotransposons that combine the activities of an autocatalytic intron RNA (a ribozyme) and an intron-encoded reverse transcriptase to insert site-specifically into DNA. They recognize DNA target sites largely by base pairing of sequences within the intron RNA...

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Detalhes bibliográficos
Main Authors: Enyeart, Peter J, Mohr, Georg, Ellington, Andrew D, Lambowitz, Alan M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898094/
https://ncbi.nlm.nih.gov/pubmed/24410776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-5-2
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