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Immuno-Histochemical Analysis of Rod and Cone Reaction to RPE65 Deficiency in the Inferior and Superior Canine Retina

Mutations in the RPE65 gene are associated with autosomal recessive early onset severe retinal dystrophy. Morphological and functional studies indicate early and dramatic loss of rod photoreceptors and early loss of S-cone function, while L and M cones remain initially functional. The Swedish Briard...

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Detalhes bibliográficos
Main Authors: Klein, Daniela, Mendes-Madeira, Alexandra, Schlegel, Patrice, Rolling, Fabienne, Lorenz, Birgit, Haverkamp, Silke, Stieger, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897682/
https://ncbi.nlm.nih.gov/pubmed/24466015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086304
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