A Lifespan Observation of a Novel Mouse Model: In Vivo Evidence Supports Aβ Oligomer Hypothesis

Transgenic mouse models are powerful tools in exploring the mechanisms of AD. Most current transgenic models of AD mimic the memory impairment and the main pathologic features, among which the formation of beta-amyloid (Aβ) plaques is considered a dominant pathologic event. Recently, Aβ oligomers ha...

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Detalhes bibliográficos
Main Authors: Zhang, Yichi, Lu, Lu, Jia, Jianping, Jia, Longfei, Geula, Changiz, Pei, Jinjing, Xu, Zhiqing, Qin, Wei, Liu, Ruiqin, Li, Dan, Pan, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897547/
https://ncbi.nlm.nih.gov/pubmed/24465766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085885
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