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Signal Intensities Derived from Different NMR Probes and Parameters Contribute to Variations in Quantification of Metabolites

We discovered that serious issues could arise that may complicate interpretation of metabolomic data when identical samples are analyzed at more than one NMR facility, or using slightly different NMR parameters on the same instrument. This is important because cross-center validation metabolomics st...

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Detalhes bibliográficos
Principais autores: Lacy, Paige, McKay, Ryan T., Finkel, Michael, Karnovsky, Alla, Woehler, Scott, Lewis, Michael J., Chang, David, Stringer, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897511/
https://ncbi.nlm.nih.gov/pubmed/24465670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085732
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