Generation of “Virtual” Control Groups for Single Arm Prostate Cancer Adjuvant Trials

It is difficult to construct a control group for trials of adjuvant therapy (Rx) of prostate cancer after radical prostatectomy (RP) due to ethical issues and patient acceptance. We utilized 8 curve-fitting models to estimate the time to 60%, 65%, … 95% chance of progression free survival (PFS) base...

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Detalhes bibliográficos
Main Authors: Jia, Zhenyu, Lilly, Michael B., Koziol, James A., Chen, Xin, Xia, Xiao-Qin, Wang, Yipeng, Skarecky, Douglas, Sutton, Manuel, Sawyers, Anne, Ruckle, Herbert, Carpenter, Philip M., Wang-Rodriguez, Jessica, Jiang, Jun, Deng, Mingsen, Pan, Cong, Zhu, Jian-guo, McLaren, Christine E., Gurley, Michael J., Lee, Chung, McClelland, Michael, Ahlering, Thomas, Kattan, Michael W., Mercola, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897405/
https://ncbi.nlm.nih.gov/pubmed/24465467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085010
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