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A Sample Selection Strategy to Boost the Statistical Power of Signature Detection in Cancer Expression Profile Studies

In case-control profiling studies, increasing the sample size does not always improve statistical power because the variance may also be increased if samples are highly heterogeneous. For instance, tumor samples used for gene expression assay are often heterogeneous in terms of tissue composition or...

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Detalhes bibliográficos
Main Authors: Jia, Zhenyu, Wang, Yipeng, Hu, Yuanjie, McLaren, Christine, Yu, Yingyan, Ye, Kai, Xia, Xiao-Qin, Koziol, James A., Lernhardt, Waldemar, McClelland, Michael, Mercola, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786411/
https://ncbi.nlm.nih.gov/pubmed/22934703
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