Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress

BACKGROUND: The innate immune response is the first line of defence against invading microorganisms and it is also activated in different neurologic/neurodegenerative pathological scenarios. As a result, the family of the innate immune toll-like receptors (TLRs) and, in particular, the genetic/pharm...

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Autores principales: Gárate, Iciar, García-Bueno, Borja, Madrigal, José Luis Muñoz, Caso, Javier R, Alou, Luis, Gómez-Lus, María Luisa, Leza, Juan Carlos
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897306/
https://ncbi.nlm.nih.gov/pubmed/24410883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-8
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