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Requirement for IL-13 Independently of IL-4 in Experimental Asthma

The pathogenesis of asthma reflects, in part, the activity of T cell cytokines. Murine models support participation of interleukin-4 (IL-4) and the IL-4 receptor in asthma. Selective neutralization of IL-13, a cytokine related to IL-4 that also binds to the α chain of the IL-4 receptor, ameliorated...

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Detalhes bibliográficos
Main Authors: Grünig, Gabriele, Warnock, Martha, Wakil, Adil E., Venkayya, Rajeev, Brombacher, Frank, Rennick, Donna M., Sheppard, Dean, Mohrs, Markus, Donaldson, Debra D., Locksley, Richard M., Corry, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897229/
https://ncbi.nlm.nih.gov/pubmed/9856950
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