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Identity Crisis: It’s Not Just Foxp3 Anymore

What does it take to make a regulatory T (Treg) cell? In this issue of Immunity, Ohkura et al. (2012) show that Treg cell-specific CpG hypomethylation and Foxp3 expression are independent events required for Treg cell development, stability and full suppressive activity.

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書目詳細資料
Main Authors: Delgoffe, Greg M., Bettini, Matthew L., Vignali, Dario A. A.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897225/
https://ncbi.nlm.nih.gov/pubmed/23159220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.10.012
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