Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens

Several carcinogenic metabolites of the carcinogen 2-acetyl-aminofluorene, especially 2-nitrosofluorene and N-hydroxy-2-aminofluorene, are potent frameshift mutagens for Salmonella typhimurium. 2-Nitrosonaphthalene, 2-nitrosophenanthrene, 4-nitroso-trans-stilbene, 4-nitrosobiphenyl, and 4-nitrosoazo...

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書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Ames, Bruce N., Gurney, E. G., Miller, James A., Bartsch, H.
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1972
主題:	Biological Sciences: Genetics
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4564203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.11.3128
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