TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures

Nuclear factor κB (NF-κB) essential modulator (NEMO), a regulatory component of the IκB kinase (IKK) complex, controls NF-κB activation through its interaction with ubiquitin chains. We show here that stimulation with interleukin-1 (IL-1) and TNF induces a rapid and transient recruitment of NEMO int...

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Bibliografiske detaljer
Main Authors: Tarantino, Nadine, Tinevez, Jean-Yves, Crowell, Elizabeth Faris, Boisson, Bertrand, Henriques, Ricardo, Mhlanga, Musa, Agou, Fabrice, Israël, Alain, Laplantine, Emmanuel
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897181/
https://ncbi.nlm.nih.gov/pubmed/24446482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307172
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