NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

An important property of NEMO, the core element of the IKK complex involved in NF-κB activation, resides in its ability to specifically recognize poly-ubiquitin chains. A small domain called NOA/UBAN has been suggested to be responsible for this property. We recently demonstrated that the C-terminal...

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Hlavní autoři: Laplantine, E, Fontan, E, Chiaravalli, J, Lopez, T, Lakisic, G, Véron, M, Agou, F, Israël, Alain
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760117/
https://ncbi.nlm.nih.gov/pubmed/19763089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.241
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