Genetic variants in the cytochrome P450 2D6 gene in the Sri Lankan population

INTRODUCTION: Cytochrome P450 2D6 (CYP2D6) enzymes are involved in the metabolism of a large number of commonly prescribed drugs such as antidepressants and cardiovascular drugs. The CYP2D6 *3, *4 and *14 variants associated with the loss of enzyme function; CYP2D6 *10 and *17 variants with reduced...

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Main Authors: Tharanga, T. D. Praveen, Jinadasa, C. M. V., Risama, M. F., Galappatthy, Priyadarshani, Jayakody, R. L., Dissanayake, Vajira H. W.
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897131/
https://ncbi.nlm.nih.gov/pubmed/24497701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.124361
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