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Incorporation of Nucleoside Probes Opposite O(6)-Methylguanine by Sulfolobus solfataricus DNA Polymerase Dpo4: Importance of Hydrogen Bonding
O(6)-Methylguanine (O(6)-MeG) is a mutagenic DNA lesion, arising from the action of methylating agents on guanine (G) in DNA. Dpo4, an archaeal low-fidelity Y-family DNA polymerase involved in translesion DNA synthesis (TLS), is a model for studying how human Y-family polymerases bypass DNA adducts....
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896954/ https://ncbi.nlm.nih.gov/pubmed/23959784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300296 |
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