Addition of Chemical and Osmotic Free Energies Through Negative Interaction of Protein-Bound Ligands
Simple free energy considerations show that an effector ligand, Y, bound to a protein can modify the standard free energy change of the reaction P - X + D - R = P - R + D - X, where P is a protein, D - R a small molecule, and X a group in the protein that interacts negatively with Y. By consideratio...
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| 發表在: | Proc Natl Acad Sci U S A |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1972
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389694/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4507618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.10.3000 |
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