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Addition of Chemical and Osmotic Free Energies Through Negative Interaction of Protein-Bound Ligands

Simple free energy considerations show that an effector ligand, Y, bound to a protein can modify the standard free energy change of the reaction P - X + D - R = P - R + D - X, where P is a protein, D - R a small molecule, and X a group in the protein that interacts negatively with Y. By consideratio...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Weber, Gregorio
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1972
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4507618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.10.3000
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