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Combinatorial gene editing in mammalian cells using ssODNs and TALENs

The regulation of gene editing is being elucidated in mammalian cells and its potential as well as its limitations are becoming evident. ssODNs carry out gene editing by annealing to their complimentary sequence at the target site and acting as primers for replication fork extension. To effect a gen...

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Sonraí Bibleagrafaíochta
Main Authors: Strouse, Bryan, Bialk, Pawel, Niamat, Rohina A., Rivera-Torres, Natalia, Kmiec, Eric B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896902/
https://ncbi.nlm.nih.gov/pubmed/24445749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03791
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