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CpG sites associated with NRP1, NRXN2 and miR-29b-2 are hypomethylated in monocytes during ageing

BACKGROUND: Ageing affects many components of the immune system, including innate immune cells like monocytes. They are important in the early response to pathogens and for their role to differentiate into macrophages and dendritic cells. Recent studies have revealed significant age-related changes...

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Détails bibliographiques
Auteurs principaux: Tserel, Liina, Limbach, Maia, Saare, Mario, Kisand, Kai, Metspalu, Andres, Milani, Lili, Peterson, Pärt
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896835/
https://ncbi.nlm.nih.gov/pubmed/24405718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-11-1
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