Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice

BACKGROUND: Spinal Toll-like receptors (TLRs) and signaling intermediaries have been implicated in persistent pain states. We examined the roles of two major TLR signaling pathways and selected TLRs in a mononeuropathic allodynia. METHODS: L5 spinal nerve ligation (SNL) was performed in wild type (W...

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Autori principali: Stokes, Jennifer A, Cheung, Jonathan, Eddinger, Kelly, Corr, Maripat, Yaksh, Tony L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896749/
https://ncbi.nlm.nih.gov/pubmed/24321498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-148
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