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Consequences of glycan truncation on Fc structural integrity

Effective characterization of protein-based therapeutic candidates such as monoclonal antibodies (mAbs) is important to facilitate their successful progression from early discovery and development stages to marketing approval. One challenge relevant to biopharmaceutical development is, understanding...

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Detalhes bibliográficos
Main Authors: Buck, Patrick M, Kumar, Sandeep, Singh, Satish K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896604/
https://ncbi.nlm.nih.gov/pubmed/24492344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26453
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