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Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition

Increasing gap junction activity in tumor cells provides a target by which to enhance antineoplastic therapies. Previously, several naturally occurring agents, including all-trans retinoic acid (ATRA) have been demonstrated to increase gap junctional intercellular communication (GJIC) in a number of...

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Main Authors: YANG, YAN, QIN, SHU-KUI, WU, QIONG, WANG, ZI-SHU, ZHENG, RONG-SHENG, TONG, XU-HUI, LIU, HAO, TAO, LIANG, HE, XIAN-DI
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896525/
https://ncbi.nlm.nih.gov/pubmed/24317203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2894
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