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Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

Methylation of CpG islands in the promoter region of genes acts as a significant mechanism of epigenetic gene silencing in head and neck cancer. In the present study, we assessed the association of epigenetic alterations of a panel of 12 genes [nucleolar protein 4 (NOL4), iroquois homeobox 1 (IRX1),...

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Detalhes bibliográficos
Main Authors: DEMOKAN, SEMRA, CHUANG, ALICE Y., PATTANI, KAVITA M., SIDRANSKY, DAVID, KOCH, WAYNE, CALIFANO, JOSEPH A.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896520/
https://ncbi.nlm.nih.gov/pubmed/24337411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2927
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