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CRISPR/Cas9-mediated genome engineering and the promise of designer flies on demand

The CRISPR/Cas9 system has attracted significant attention for its potential to transform genome engineering. We and others have recently shown that the RNA-guided Cas9 nuclease can be employed to engineer the Drosophila genome, and that these modifications are efficiently transmitted through the ge...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gratz, Scott J, Wildonger, Jill, Harrison, Melissa M, O'Connor-Giles, Kate M
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Landes Bioscience 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896497/
https://ncbi.nlm.nih.gov/pubmed/24088745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.26566
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