Bcl2 Deficiency Activates FoxO through Akt Inactivation and Accelerates Osteoblast Differentiation

Osteoblast apoptosis plays an important role in bone development and maintenance, and is in part responsible for osteoporosis in sex steroid deficiency, glucocorticoid excess, and aging. Although Bcl2 subfamily proteins, including Bcl2 and Bcl-XL, inhibit apoptosis, the physiological significance of...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Moriishi, Takeshi, Kawai, Yosuke, Komori, Hisato, Rokutanda, Satoshi, Eguchi, Yutaka, Tsujimoto, Yoshihide, Asahina, Izumi, Komori, Toshihisa
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896485/
https://ncbi.nlm.nih.gov/pubmed/24466179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086629
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы