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Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold
The OB-fold is a small, versatile single-domain protein binding module that occurs in all forms of life, where it binds protein, carbohydrate, nucleic acid and small-molecule ligands. We have exploited this natural plasticity to engineer a new class of non-immunoglobulin alternatives to antibodies w...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896448/ https://ncbi.nlm.nih.gov/pubmed/24465865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086050 |
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