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Intraflagellar Transport Gene Expression Associated with Short Cilia in Smoking and COPD

Smoking and COPD are associated with decreased mucociliary clearance, and healthy smokers have shorter cilia in the large airway than nonsmokers. We hypothesized that changes in cilia length are consistent throughout the airway, and we further hypothesized that smokers with COPD have shorter cilia t...

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Detalhes bibliográficos
Main Authors: Hessel, Justina, Heldrich, Jonna, Fuller, Jennifer, Staudt, Michelle R., Radisch, Sharon, Hollmann, Charleen, Harvey, Ben-Gary, Kaner, Robert J., Salit, Jacqueline, Yee-Levin, Jenny, Sridhar, Sriram, Pillai, Sreekumar, Hilton, Holly, Wolff, Gerhard, Bitter, Hans, Visvanathan, Sudha, Fine, Jay, Stevenson, Christopher S., Crystal, Ronald G., Tilley, Ann E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896362/
https://ncbi.nlm.nih.gov/pubmed/24465567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085453
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