Intraflagellar Transport Gene Expression Associated with Short Cilia in Smoking and COPD

Smoking and COPD are associated with decreased mucociliary clearance, and healthy smokers have shorter cilia in the large airway than nonsmokers. We hypothesized that changes in cilia length are consistent throughout the airway, and we further hypothesized that smokers with COPD have shorter cilia t...

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Main Authors: Hessel, Justina, Heldrich, Jonna, Fuller, Jennifer, Staudt, Michelle R., Radisch, Sharon, Hollmann, Charleen, Harvey, Ben-Gary, Kaner, Robert J., Salit, Jacqueline, Yee-Levin, Jenny, Sridhar, Sriram, Pillai, Sreekumar, Hilton, Holly, Wolff, Gerhard, Bitter, Hans, Visvanathan, Sudha, Fine, Jay, Stevenson, Christopher S., Crystal, Ronald G., Tilley, Ann E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896362/
https://ncbi.nlm.nih.gov/pubmed/24465567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085453
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