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Mechanism of Action of Bacitracin: Complexation with Metal Ion and C(55)-Isoprenyl Pyrophosphate

The inhibition by bacitracin of the enzymatic dephosphorylation of C(55)-isoprenyl pyrophosphate is abolished by the addition of chelating agents. If, however, the chelating agent is added after a preincubation of bacitracin with a divalent cation and the lipid substrate, then its addition has littl...

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Detalhes bibliográficos
Main Authors: Stone, K. John, Strominger, Jack L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC389626/
https://ncbi.nlm.nih.gov/pubmed/4332017
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